On January 23, 2026, Natalie Salcedo faced Chihiro Sawada at ONE Fight Night 39, suffering her first professional MMA loss via unanimous decision. The defeat brought an end to her previously unbeaten record and marked a defining moment in her competitive career.
The bout unfolded on a high-profile stage under the ONE Championship banner, underscoring Salcedo's established presence within the promotion. A first loss against a skilled opponent at this level carries significant weight — not as a setback, but as a catalyst. Experiences of this nature often sharpen a fighter's technical game, refine their strategic approach, and fuel the kind of focused development that elevates careers over the long term.